Tatia M.C. Lee(李湄珍)
Chair Professor
Office: Rm. 656, Jockey Club Tower, Centennial Campus, HKU
Phone: (852) 3917 8394
Email: tmclee@hku.hk
HKU Scholars Hub

Research Interests

Prof. Lee is a Chair Professor of Psychology. Her research interests are:
- Neural mechanisms underlying social cognitive affective functions and response regulation.
- Neuroplasticity and neuro-cognitive recovery from brain pathologies.

Selected Publications

Shao R, Sun D, Lee TMC. The interaction of perceived control and gambler’s fallacy in risky decision making: An fMRI study. Human Brain Mapping, 2016; 37: 1218-1234.

Wong NML, Liu HL, Lin C, Huang CM, Wai YY, Lee SH, Lee TMC. Loneliness in late-life depression: Structural and functional connectivity during affective processing. Psychological Medicine (in press)

Sun DL, Lee TMC, Wang ZX, Chan CCH. Unfolding the Spatial and Temporal Neural Processing of Making Dishonest Choices. PLoS One, 11: e0153660. 

Terrighena EL, Shao R, Lee TMC. The impact of concurrent cognitive processing on cold pain perception:  Implications for pain management and its neurobiological basis. Applied Neuropsychology (in press).

Yu J and Lee TMC. Cognitive flexibility and changes in hopelessness across time: A moderation hypothesis. Applied Neuropsychology: Adult. Epub ahead of print

Yu J, Lam CLM, Lee TMC. Mild Cognitive Impairment in a Chinese community is associated with loneliness even after controlling for depression. International Geriatrics (in press).

Lam BYH, Raine A, Lee TMC. Effect of theory of mind and peer victimization on the schizotypy–aggression relationship. NPJ Schizophrenia. 2016: 16001

Wong NML, Cheung S-H, Chan CCH, Zeng H, Li Y-P, So K-F, and Lee TMC. Diffusivity of the uncinate fasciculus in heroin users relates to their levels of anxiety. Transl Psychiatry. 2015 Apr 28; 5:e554. Lam BYH, Yang Y, Raine A, Lee TMC. Neural mediator of the schizotypy-antisocial behavior relationship. Transl Psychiatry. 2015 Nov 3; 5:e669.

Lau WKW, Leung MK, Chan CCH, Wong SSY, Lee TMC. Can the neural–cortisol association be moderated by experience-induced changes in awareness? Sci Rep. 2015 Nov 18; 5:16620.

Lin K, Xu G, Lu W, Ouyang H, Dang Y, Guo Y, So KF, Lee TMC. Neuropsychological performance of patients with soft bipolar spectrum disorders. Bipolar Disord. 2015 Mar; 17(2):194-204.

Cheng GLF, Liu YP, Chan CCH, So KF, Zeng H, Lee TMC. Neurobiological underpinnings of sensation seeking trait in heroin abusers. European Neuropsychopharmacology. 2015; 25: 1968-1980.

Leung NTY, Tam HMK, Chu LW, Kwok TCY, Chan F, Lam LCW, Woo J, Lee TMC. Neural plastic effects of cognitive training on aging brain. Neural Plast. 2015; 2015: 535618.

Tao Q, Chan CCH, Luo YJ, Li JJ, Ting KH, Wang J, Lee TMC. How Does Experience Modulate Auditory Spatial Processing in Individuals with Blindness? Brain Topography. 2015 May; 28(3):506-19.

Shao R, Zhang HJ, Lee TMC. The neural basis of social risky decision making in females with Major Depressive Disorder. Neuropsychologia. 2015 Jan; 67:100-10.

Sun D, Chan CC, Hu Y, Wang Z, Lee TMC. Neural Correlates of Outcome Processing Post Dishonest Choice: An fMRI and ERP study. Neuropsychologia. 2015 Jan 10; 68C:148-157.

Sun DL, Chan CCH, Fan JT, Wu Y, Lee TMC. Are Happy Faces Attractive? The Roles of Early versus Late Processing. Frontier Psychology (Cognitive Science). 2015 Nov 30; 6:1812.  

Cheng GLF, Lee TMC. Altering Risky Decision Making: Influence of Impulsivity on the Neuromodulation of Prefrontal Cortex. Social Neuroscience. 2015 Sep; 17:1-12.

Tao Q, Chan CCH, Luo YJ, Li JJ, Ting KH, Wang J, Lee TMC. How Does Experience Modulate Auditory Spatial Processing in Individuals with Blindness? Brain Topography. 2015 May; 28(3):506-19.

Hou WK, Lau KM, Ng SM, Lee TMC, Cheugn HYS, Shum TCY, Cheng ACK. Psychological Detachment and Savoring in Adaptation to Cancer Caregiving. Psycho-oncology. 2015 Oct 30. doi: 10.1002/pon.4019.

Leung M-K, Chang CCH, Jing Y, Lee C-F, So K-F, and Lee TMC. Enhanced Amygdala-Cortical Functional Connectivity in Meditators, Neuroscience Letters. 2015; 590: 106-110

Ho NSP, Sun DL, Ting KH, Chan CCH, Lee TMC. Mindfulness trait predicts neurophysiological reactivity associated with negativity bias: An ERP study. Evidence-Based Complementary and Alternative Medicine. 2015; 2015:1-15.

Yesudas EH, Lee TMC. The role of cingulate cortex in vicarious pain. Biomed Res Int, 2015; 2015:719615

Yu JH, Tam HMK, Lee TMC. Traumatic Brain Injury Rehabilitation in Hong Kong: A Review of Research and Practice. Behavioral Neurology, 2015; 2015:274326.

Lin K, Xu G, Wong NM, Wu H, Li T, Lu W, Chen K, Chen X, Lai B, Zhong L, So K-F, Lee TM. A Multi-Dimensional and Integrative Approach to Examining the High-Risk and Ultra-High-Risk Stages of Bipolar Disorder, EbioMedicine , 2015; July 10; 2(8): 917-926

Lee TMC, Sun DL, Wong NML, Shao R, Men W, Ge J, So KF, Gao JH, Chan CCH.  A pontine region is a neural correlate of the human affective processing network. EbioMedicine, 2015 Oct 20;2(11):1799-1805

Sun DL, Lee TMC, Chan CCH. Unfolding the spatial and temporal neural processing of lying about face familiarity. Cerebral Cortex. 2013;25(4):927-936. doi:10.1093/cercor/bht284

Lee TM, Wong ML, Lau BW, Lee JC, Yau SY, So KF. Aerobic exercise interacts   with   neurotrophic   factors   to   predict   cognitive   functioning   in adolescents. Psychoneuroendocrinology. 2014 Jan; 39:214-24.

Lin K, Xu G, Lu W, Ouyang H, Dang Y, Lorenzo-Seva U, Guo Y, Bessonov D, Akiskal HS, So KF, and Lee TMC. Neuropsychological performance in melancholic, atypical and undifferentiated major depression during depressed and remitted states: a prospective longitudinal study. J Affect Disord. 2014; 168:184-91.

Gao JL, Cheung RTF, Chan YS, Chu LW, Mak HKF, Lee TMC. The Relevance of Short-Range Fibers to Cognitive Efficiency and Brain Activation in Aging and Dementia. PLoS One. 2014; 9 (4): e90307

Lam BYH, Raine A, Lee TMC. The relationship between neurocognition and symptomatology in people with schizophrenia: social cognition as the mediator. Bmc Psychiatr.  2014 May 13; 14:138.

Leung NTY, Lo MM, Lee TMC. Potential therapeutic effects of meditation for treating affective dysregulation. Evid Based Complement Alternat Med. 2014; 2014:402718.  2.175

Tam HMK, Lam CLM, Huang H, Wang B, Lee TMC. Age-related Difference in Relationships between Cognitive Processing Speed and General Cognitive Status. Appl Neuropsychol Adult. 2014 Jun; 13:1-6.

Shao R, Lee TMC. Aging and risk-taking: Towards an integration of cognitive, emotional and neurobiological perspectives. Neuroscience and Neuroeconomics. 2014; 3: 47-62.

Wong NML, Lee TMC. Genetic and neural relationships underpinning impulsivity. International Journal of Psychological Research. 2013; 6:80-93

Cheng GLF, Zeng H, Leung MK, Zhang HJ, Lau BWM, Liu YP, Liu GX, Sham PC, Chan CCH, Lee TMC. (2013) Heroin abuse accelerates biological aging: A novel insight from telomerase and brain imaging interaction. Translational Psychiatry (Nature Publishing Group). May 21;3:e260. doi: 10.1038/tp.2013.36.(pdf)

Lee TMC, Leung MK, Lee TMY, Raine A, Chan CCH. (2013) I want to lie about not knowing you, but my precuneus refuses to cooperate. Scientific Reports (Nature Publishing Group). 2013; 3:1636. DOI:10.1038/srep01636.(pdf)

Leung MK, Chan CCH, Jing Y, Lee CF, So KF, Lee TMC. (2013) Increased gray-matter volume in the right angular and posterior parahippocampal gyri in loving-kindness meditators. Social Cognitive & Affective Neuroscience. 2013;8:34-49. (pdf)

Lee TMC, Sun DL, Leung MK, Chu LW, Keysers C. (2013) Neural activities during affective processing in people with Alzheimer's disease. Neurobiology of Aging. 34:706-715. (pdf)

Chan CCH, Wong AWK, Ting KH, Whitfield-Gabrieli S, He J, Lee TMC. (2012) Cross Auditory-Spatial Learning in Early-Blind Individuals. Human Brain Mapping. 33: 2714-2727. (pdf)

Lee TMC, Lee TMF, Raine A, Chan CC. (2010). Lying about the Valence of Affective Pictures: An fMRI Study. PLos ONE. 2010 Aug 25;5(8):e12291. (pdf)

Lee TMC, Ip AK, Wang K, Xi CH, Hu PP, Mak HK, Han SH, Chan CC. (2010). Faux pas deficits in people with medial frontal lesions as related to impaired understanding of a speaker’s mental state. Neuropsychologia, 48:1670-1676. (pdf)

Chan SC, Raine A, Lee TMC. (2010). Attentional bias towards negative affect stimuli and reactive aggression in male batterers. Psychiatry Research, 176: 246–249. (pdf)

Lee TMC, Chan CC, Leung AW, Fox PT, Gao JH. (2009). Sex-related differences in neural activity during risk taking: An fMRI study.Cerebral Cortex, 19:1303-1312. (pdf)

Lee TM, Guo LG, Shi HZ, Li YZ, Luo YJ, Sung CY, Chan CC, Lee TMC. (2009). Neural correlates of Traditional Chinese Medicine induced advantageous risk-taking decision making. Brain and Cognition, 71 (3): 354-361. (pdf)

Lee TMC, Chan SC, Raine A. (2008). Strong limbic and weak frontal activation to aggressive stimuli in spouse abusers. Molecular Psychiatry, 13: 655-660. (pdf) (Findings also reported and discussed in Science:321 1023.)

To see more publications of Prof. TMC, Lee , please click here.