You-Qiang SONG (宋又强)
Associate Professor
Office: L3-63, Laboratory Block, 21 Sassoon Road, Hong Kong
Phone: (852) 3917 9245
HKU Scholars Hub

Research Interests

• Genetics of neurodegenerative diseases, such Alzheimer’s disease
• The molecular signaling pathways linking A-beta to phosphorylation of tau in Alzheimer disease

Selected Publications:

  1. Plani-Lam JH, Chow TC, Siu KL, Chau WH, Ng MH, Bao S, Ng CT, Sham P, Shum DK,  Ingley E, Jin DY, Song YQ. PTPN21 exerts pro-neuronal survival and neuritic elongation via ErbB4/NRG3 signaling. Int J Biochem Cell Biol. 2015 Apr;61:53-62.

  2. Zhou XY, Bao SY, Wang BB, Zhang XG, and Song YQ: A Practical Guide for Mapping Short Reads. Shomron, Noam (eds.) Deep Sequencing Data Analysis. Methods in Molecular Biology, Springer 2013, pp93-112

  3. Li MX, Kwan JS, Bao SY, Yang W, Ho SL, Song YQ, Sham PC. Predicting mendelian disease-causing non-synonymous single nucleotide variants in exome sequencing studies. PLoS Genet. 2013 Jan;9(1):e1003143.

  4. Chen LH, Kao PY, Fan YH, Ho DT, Chan CS, Yik PY, Ha JC, Chu LW, Song YQ. Polymorphisms of CR1, CLU and PICALM confer susceptibility of Alzheimer's disease in a southern Chinese population. Neurobiol Aging. 2012 Jan, 33(1):210.e1-7.

  5. Li Y, Chu LW, Wang B, Yik PY, Huriletemuer, Jin DY, Ma X, Song YQ. (2010)  CYP46A1 functional promoter haplotypes decipher genetic susceptibility to Alzheimer’s disease. J Alzheimers Dis. 21(4):1311-23.

  6. Bao S, Jiang R, Kwan W, Wang B, Ma X, Song YQ. Evaluation of next-generation sequencing software in mapping and assembly. J Hum Genet. 2011 56, 406–414.